Is breast cancer hereditary
Do sisters and daughters of breast cancer patients have a high risk of developing cancer? How to prevent and treat it early? These questions are often asked by many people.
5% of patients with hereditary breast cancer
Breast cancer, like most malignant tumors, is caused by the combined effects of environmental and genetic factors. In the occurrence mechanism of breast cancer, genetic factors only account for a small part.
Studies have shown that only about 5% of patients with hereditary breast cancer have been found, which only accounts for a small part of all breast cancer patients.
What is familial breast cancer
Familial breast cancer refers to a type of breast cancer with familial aggregation. In other words, if two blood-related members in a family suffer from breast cancer, it can be called familial breast cancer.
Breast cancer with clear genetic factors is called hereditary breast cancer. This part of breast cancer accounts for 5%-10% of the entire breast population. This type of breast cancer has the characteristics of early onset, bilateral onset, and multi-center lesions.
What are the causes of familial breast cancer
Most hereditary breast cancers have familial clustering and belong to familial breast cancer; however, a small number of hereditary breast cancers are distributed as sporadic and have no family history. This may be because the mutated genes related to breast cancer are carried by male family members and cannot form a breast cancer phenotype.
Most hereditary breast cancers are related to breast cancer susceptibility genes (BRCA-1, BRCA-2). In addition to BRCA-1 and BRCA-2, there are also p53, PTEN, etc. Breast cancers related to these gene mutations are classified as hereditary breast cancer. Like all hereditary breast cancers, most BRCA-1 and BRCA-2 related breast cancers belong to familial breast cancers, and some are sporadic.
How women take care of their breasts to avoid breast cancer? Click here if you want to know more about it.