Risk factors for gastric cancer include Helicobacter pylori, smoking, high-salt diet and other dietary factors. Smokers have a 50%-60% increased risk of gastric cancer.
It is estimated that 11% of gastric malignancies worldwide are closely related to smoking.
Tobacco contains a variety of carcinogens
Experts have conducted a large number of epidemiological studies, most of which show that smoking is positively correlated with gastric cancer.
Tobacco and tobacco smoke contain a variety of carcinogens such as polycyclic aromatic hydrocarbons and nitrosamines, and the carcinogenicity of these two substances has been confirmed in experimental animals.
Recent studies have also found that tobacco smoke contains free radicals, which can cause tissue cancer by destroying genetic genes, damaging cell membranes and reducing immune function.
These substances can dissolve in saliva, enter the stomach with swallowing, and cause cancer with long-term effects as the amount of smoking increases and the duration of smoking increases.
Carotenoids and vitamin C have the effect to anti-cancer
Smoking can reduce the levels of carotenoids and vitamin C in the human body, and the latter two are protective agents with anti-cancer effects on the body.
Smoking patients often have Helicobacter pylori infection, and the two together promote the occurrence of atrophic gastritis.
It takes 20 years for smokers to reduce their risk of gastric cancer to the level of normal people after quitting smoking.
Smoking during meals can damage gastric mucosa.
Tobacco and tobacco smoke contain a variety of carcinogens and cancer-promoting substances, such as benzopyrene, dimethylnitrosamine, phenolic compounds, radioactive elements, etc. Other serious harmful substances include nicotine, carbon monoxide and tobacco tar.
Smoking during meals can swallow harmful substances in tobacco with food and contact with gastric mucosa. Tredaniel’s analysis results show that smokers have a 1.5-1.6 risk ratio for gastric cancer compared with non-smokers, and there is a dose relationship.
Tobacco smoke can damage genetic genes
In recent years, research has also found that tobacco smoke contains free radicals, which can damage genetic genes, damage cell membranes and reduce immunity, and promote tissue cancer.
These substances can dissolve in saliva and enter the stomach with swallowing, and due to the increase in smoking volume and smoking time, long-term effects can cause gastric cancer.
Experts conducted a matched case-control study, 303 new cases of gastric cancer and 303 healthy people. The results showed that the incidence of gastric cancer showed an increasing trend with the increase in years of smoking, the amount of cigarettes smoked per day and the number of years of smoking.